Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Col2a1  collagen, type II, alpha 1   (Synonyms: Col2, Col2a, Col2a-1, Del1, Lpk, M100413, M100856, Rgsc413, Rgsc856)
Results	Reference
1*	J:294897 Ankamreddy H, Koo H, Lee YJ, Bok J, CXCL12 is required for stirrup-shaped stapes formation during mammalian middle ear development. Dev Dyn. 2020 Sep;249(9):1117-1126
1*	J:43437 Apte SS, Fukai N, Beier DR, Olsen BR, The matrix metalloproteinase-14 (MMP-14) gene is structurally distinct from other MMP genes and is co-expressed with the TIMP-2 gene during mouse embryogenesis. J Biol Chem. 1997 Oct 10;272(41):25511-7
1	J:119152 Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell. 2007 Mar;12(3):377-89
1*	J:56413 Bachner D, Ahrens M, Betat N, Schroder D, Gross G, Developmental expression analysis of murine autotaxin (ATX). Mech Dev. 1999 Jun;84(1-2):121-5
1	J:128020 Barbosa AC, Funato N, Chapman S, McKee MD, Richardson JA, Olson EN, Yanagisawa H, Hand transcription factors cooperatively regulate development of the distal midline mesenchyme. Dev Biol. 2007 Oct 1;310(1):154-68
1	J:99990 Barna M, Pandolfi PP, Niswander L, Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development. Nature. 2005 Jul 14;436(7048):277-81
1*	J:296399 Bartoletti G, Dong C, Umar M, He F, Pdgfra regulates multipotent cell differentiation towards chondrocytes via inhibiting Wnt9a/beta-catenin pathway during chondrocranial cartilage development. Dev Biol. 2020 Oct 1;466(1-2):36-46
1	J:297087 Bian Q, Cheng YH, Wilson JP, Su EY, Kim DW, Wang H, Yoo S, Blackshaw S, Cahan P, A single cell transcriptional atlas of early synovial joint development. Development. 2020 Jul 20;147(14):dev185777
1*	J:32246 Cheah KS, Lau ET, Au PK, Tam PP, Expression of the mouse alpha 1(II) collagen gene is not restricted to cartilage during development. Development. 1991 Apr;111(4):945-53
1	J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21
1*	J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21
1*	J:89221 Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A, Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev Dyn. 2004 Apr;229(4):826-34
1	J:230611 Dierker T, Bachvarova V, Krause Y, Li JP, Kjellen L, Seidler DG, Vortkamp A, Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. Matrix Biol. 2016 Jan;49:82-92
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:237001 Duan X, Bradbury SR, Olsen BR, Berendsen AD, VEGF stimulates intramembranous bone formation during craniofacial skeletal development. Matrix Biol. 2016 May-Jul;52-54:127-40
1	J:221660 Eyal S, Blitz E, Shwartz Y, Akiyama H, Schweitzer R, Zelzer E, On the development of the patella. Development. 2015 May 15;142(10):1831-9
1	J:330128 Fabik J, Psutkova V, Machon O, Meis2 controls skeletal formation in the hyoid region. Front Cell Dev Biol. 2022;10:951063
1	J:295760 Felsenthal N, Rubin S, Stern T, Krief S, Pal D, Pryce BA, Schweitzer R, Zelzer E, Development of migrating tendon-bone attachments involves replacement of progenitor populations. Development. 2018 Dec 18;145(24):dev165381
1*	J:58583 Fukada K, Shibata S, Suzuki S, Ohya K, Kuroda T, In situ hybridisation study of type I, II, X collagens and aggrecan mRNas in the developing condylar cartilage of fetal mouse mandible. J Anat. 1999 Oct;195(Pt 3):321-9
1	J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57
1	J:191689 Gross S, Krause Y, Wuelling M, Vortkamp A, Hoxa11 and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 and Shox2 in mice. PLoS One. 2012;7(8):e43553
1*	J:138379 Gu S, Wei N, Yu L, Fei J, Chen Y, Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice. Mech Dev. 2008 Aug;125(8):729-42
1	J:150187 Guo X, Mak KK, Taketo MM, Yang Y, The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One. 2009;4(6):e6067
1	J:300927 Han X, Feng J, Guo T, Loh YE, Yuan Y, Ho TV, Cho CK, Li J, Jing J, Janeckova E, He J, Pei F, Bi J, Song B, Chai Y, Runx2-Twist1 interaction coordinates cranial neural crest guidance of soft palate myogenesis. Elife. 2021 Jan 22;10:e62387
1	J:203056 Hines EA, Jones MK, Verheyden JM, Harvey JF, Sun X, Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19444-9
1	J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42
1	J:90584 Horiki M, Imamura T, Okamoto M, Hayashi M, Murai J, Myoui A, Ochi T, Miyazono K, Yoshikawa H, Tsumaki N, Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia. J Cell Biol. 2004 Jun 10;165(3):433-45
1*	J:42584 Huang LF, Fukai N, Selby PB, Olsen BR, Mundlos S, Mouse clavicular development: analysis of wild-type and cleidocranial dysplasia mutant mice. Dev Dyn. 1997 Sep;210(1):33-40
1	J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13
1*	J:306544 Hyde G, Boot-Handford RP, Wallis GA, Col2a1 lineage tracing reveals that the meniscus of the knee joint has a complex cellular origin. J Anat. 2008 Nov;213(5):531-8
1	J:122506 Hyde G, Dover S, Aszodi A, Wallis GA, Boot-Handford RP, Lineage tracing using matrilin-1 gene expression reveals that articular chondrocytes exist as the joint interzone forms. Dev Biol. 2007 Apr 15;304(2):825-33
1*	J:171508 Ikegami D, Akiyama H, Suzuki A, Nakamura T, Nakano T, Yoshikawa H, Tsumaki N, Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development. 2011 Apr;138(8):1507-19
1*	J:140470 Imuta Y, Nishioka N, Kiyonari H, Sasaki H, Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124). Dev Dyn. 2008 Dec 18;238(1):210-222
1	J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47
1*	J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27
1	J:154905 Joeng KS, Long F, The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization. Development. 2009 Dec;136(24):4177-85
1	J:129783 Kaback LA, Soung do Y, Naik A, Smith N, Schwarz EM, O'Keefe RJ, Drissi H, Osterix/Sp7 regulates mesenchymal stem cell mediated endochondral ossification. J Cell Physiol. 2008 Jan;214(1):173-82
1	J:148688 Kahn J, Shwartz Y, Blitz E, Krief S, Sharir A, Breitel DA, Rattenbach R, Relaix F, Maire P, Rountree RB, Kingsley DM, Zelzer E, Muscle contraction is necessary to maintain joint progenitor cell fate. Dev Cell. 2009 May;16(5):734-43
1	J:194035 Kan A, Tabin CJ, c-Jun is required for the specification of joint cell fates. Genes Dev. 2013 Mar 1;27(5):514-24
1	J:94393 Karreth F, Hoebertz A, Scheuch H, Eferl R, Wagner EF, The AP1 transcription factor Fra2 is required for efficient cartilage development. Development. 2004 Nov;131(22):5717-25
1	J:162579 Kashiwagi A, Schipani E, Fein MJ, Greer PA, Shimada M, Targeted deletion of Capn4 in cells of the chondrocyte lineage impairs chondrocyte proliferation and differentiation. Mol Cell Biol. 2010 Jun;30(11):2799-810
1*	J:53540 Kim IS, Otto F, Zabel B, Mundlos S, Regulation of chondrocyte differentiation by Cbfa1. Mech Dev. 1999 Feb;80(2):159-70
1*	J:125386 Kim JS, Ryoo ZY, Chun JS, Cytokine-like 1 (CYTL1) Regulates the Chondrogenesis of Mesenchymal Cells. J Biol Chem. 2007 Oct 5;282(40):29359-67
1*	J:158147 Kinoshita M, Era T, Jakt LM, Nishikawa S, The novel protein kinase Vlk is essential for stromal function of mesenchymal cells. Development. 2009 Jun;136(12):2069-79
1	J:121700 Kolanczyk M, Kossler N, Kuhnisch J, Lavitas L, Stricker S, Wilkening U, Manjubala I, Fratzl P, Sporle R, Herrmann BG, Parada LF, Kornak U, Mundlos S, Multiple roles for neurofibromin in skeletal development and growth. Hum Mol Genet. 2007 Apr 15;16(8):874-86
1	J:144711 Kuss P, Villavicencio-Lorini P, Witte F, Klose J, Albrecht AN, Seemann P, Hecht J, Mundlos S, Mutant Hoxd13 induces extra digits in a mouse model of synpolydactyly directly and by decreasing retinoic acid synthesis. J Clin Invest. 2009 Jan;119(1):146-56
1*	J:67153 Long F, Schipani E, Asahara H, Kronenberg H, Montminy M, The CREB family of activators is required for endochondral bone development. Development. 2001 Feb;128(4):541-50
1*	J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73
1	J:134987 Mak KK, Kronenberg HM, Chuang PT, Mackem S, Yang Y, Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy. Development. 2008 Jun;135(11):1947-56
1	J:214967 Mangiavini L, Merceron C, Araldi E, Khatri R, Gerard-O'Riley R, Wilson TL, Rankin EB, Giaccia AJ, Schipani E, Loss of VHL in mesenchymal progenitors of the limb bud alters multiple steps of endochondral bone development. Dev Biol. 2014 Sep 1;393(1):124-36
1	J:197791 Masago Y, Hosoya A, Kawasaki K, Kawano S, Nasu A, Toguchida J, Fujita K, Nakamura H, Kondoh G, Nagata K, The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation. J Cell Sci. 2012 Mar 1;125(Pt 5):1118-28
1	J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682
1	J:182340 Michikami I, Fukushi T, Tanaka M, Egusa H, Maeda Y, Ooshima T, Wakisaka S, Abe M, Kruppel-like factor 4 regulates membranous and endochondral ossification. Exp Cell Res. 2012 Feb 15;318(4):311-25
1	J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26
1*	J:264474 Mya N, Furutera T, Okuhara S, Kume T, Takechi M, Iseki S, Transcription factor Foxc1 is involved in anterior part of cranial base formation. Congenit Anom (Kyoto). 2018 Sep;58(5):158-166
1	J:217206 Neufeld SJ, Wang F, Cobb J, Genetic interactions between Shox2 and Hox genes during the regional growth and development of the mouse limb. Genetics. 2014 Nov;198(3):1117-26
1*	J:14821 Ng LJ, Tam PP, Cheah KS, Preferential expression of alternatively spliced mRNAs encoding type II procollagen with a cysteine-rich amino-propeptide in differentiating cartilage and nonchondrogenic tissues during early mouse development. Dev Biol. 1993 Oct;159(2):403-17
1*	J:38926 Ng LJ, Wheatley S, Muscat GE, Conway-Campbell J, Bowles J, Wright E , Bell DM , Tam PP , Cheah KS , Koopman P, SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev Biol. 1997 Mar 1;183(1):108-21
1	J:316655 Oh SK, Shin JO, Baek JI, Lee J, Bae JW, Ankamerddy H, Kim MJ, Huh TL, Ryoo ZY, Kim UK, Bok J, Lee KY, Pannexin 3 is required for normal progression of skeletal development in vertebrates. FASEB J. 2015 Nov;29(11):4473-84
1*	J:306318 Ono K, Hata K, Nakamura E, Ishihara S, Kobayashi S, Nakanishi M, Yoshida M, Takahata Y, Murakami T, Takenoshita S, Komori T, Nishimura R, Yoneda T, Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2. Commun Biol. 2021 Mar 11;4(1):326
1	J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41
1	J:135374 Patra D, Xing X, Davies S, Bryan J, Franz C, Hunziker EB, Sandell LJ, Site-1 protease is essential for endochondral bone formation in mice. J Cell Biol. 2007 Nov 19;179(4):687-700
1	J:51288 Pellegrini M, Pilia G, Pantano S, Lucchini F, Uda M, Fumi M, Cao A, Schlessinger D, Forabosco A, Gpc3 expression correlates with the phenotype of the Simpson-Golabi-Behmel syndrome. Dev Dyn. 1998 Dec;213(4):431-9
1	J:134727 Provot S, Zinyk D, Gunes Y, Kathri R, Le Q, Kronenberg HM, Johnson RS, Longaker MT, Giaccia AJ, Schipani E, Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development. J Cell Biol. 2007 May 7;177(3):451-64
1	J:303230 Ray AT, Mazot P, Brewer JR, Catela C, Dinsmore CJ, Soriano P, FGF signaling regulates development by processes beyond canonical pathways. Genes Dev. 2020 Dec 1;34(23-24):1735-1752
1*	J:116229 Roulet M, Ruggiero F, Karsenty G, Leguellec D, A comprehensive study of the spatial and temporal expression of the col5a1 gene in mouse embryos: a clue for understanding collagen V function in developing connective tissues. Cell Tissue Res. 2007 Feb;327(2):323-32
1*	J:149737 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ, The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
1	J:142447 Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S, The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: Findings in murine models and in human disease. Arthritis Rheum. 2008 Sep;58(9):2764-75
1*	J:39853 Savontaus M, Ihanamaki T, Metsaranta M, Vuorio E, Sandberg-Lall M, Localization of type II collagen mRNA isoforms in the developing eyes of normal and transgenic mice with a mutation in type II collagen gene. Invest Ophthalmol Vis Sci. 1997 Apr;38(5):930-42
1	J:44842 Savontaus M, Metsaranta M, Vuorio E, Mutation in type II collagen gene disturbs spinal development and gene expression patterns in transgenic Del1 mice. Lab Invest. 1997 Dec;77(6):591-600
1*	J:37148 Savontaus M, Metsranta M, Vuorio E, Retarded skeletal development in transgenic mice with a type II collagen mutation. Am J Pathol. 1996 Dec;149(6):2169-82
1	J:95068 Savontaus M, Rintala-Jamsa M, Morko J, Ronning O, Metsaranta M, Vuorio E, Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene. Orthod Craniofac Res. 2004 Nov;7(4):216-26
1*	J:207837 Schmid R, Bosserhoff AK, Redundancy in regulation of chondrogenesis in MIA/CD-RAP-deficient mice. Mech Dev. 2014 Feb;131:24-34
1	J:279005 Schroeder N, Wuelling M, Hoffmann D, Brand-Saberi B, Vortkamp A, Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones. PLoS One. 2019;14(8):e0218230
1*	J:143455 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev. 2008 Oct 1;22(19):2645-50
1*	J:83132 Settle SH Jr, Rountree RB, Sinha A, Thacker A, Higgins K, Kingsley DM, Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol. 2003 Feb 1;254(1):116-30
1	J:286313 Shea CA, Rolfe RA, McNeill H, Murphy P, Localization of YAP activity in developing skeletal rudiments is responsive to mechanical stimulation. Dev Dyn. 2020 Apr;249(4):523-542
1	J:330577 Shin M, Mori S, Mizoguchi T, Arai A, Kajiya H, Okamoto F, Bartlett JD, Matsushita M, Udagawa N, Okabe K, Mesenchymal cell TRPM7 expression is required for bone formation via the regulation of chondrogenesis. Bone. 2022 Oct 7;166:116579
1	J:239547 Sivakamasundari V, Kraus P, Sun W, Hu X, Lim SL, Prabhakar S, Lufkin T, A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development. Biol Open. 2017 Feb 15;6(2):187-199
1	J:95959 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'keefe RJ, Stein GS, Drissi MH, Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr;203(1):133-43
1	J:159823 Sohaskey ML, Jiang Y, Zhao JJ, Mohr A, Roemer F, Harland RM, Osteopotentia regulates osteoblast maturation, bone formation, and skeletal integrity in mice. J Cell Biol. 2010 May 3;189(3):511-25
1	J:137353 Sohaskey ML, Yu J, Diaz MA, Plaas AH, Harland RM, JAWS coordinates chondrogenesis and synovial joint positioning. Development. 2008 Jul;135(13):2215-20
1	J:48561 Solloway MJ, Dudley AT, Bikoff EK, Lyons KM, Hogan BL, Robertson EJ, Mice lacking Bmp6 function. Dev Genet. 1998;22(4):321-39
1*	J:57297 St-Jacques B, Hammerschmidt M, McMahon AP, Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation [published erratum appears in Genes Dev 1999 Oct 1;13(19):2617]. Genes Dev. 1999 Aug 15;13(16):2072-86
1*	J:54643 Storm EE, Kingsley DM, GDF5 coordinates bone and joint formation during digit development. Dev Biol. 1999 May 1;209(1):11-27
1	J:199574 Takahashi Y, Yasuhiko Y, Takahashi J, Takada S, Johnson RL, Saga Y, Kanno J, Metameric pattern of intervertebral disc/vertebral body is generated independently of Mesp2/Ripply-mediated rostro-caudal patterning of somites in the mouse embryo. Dev Biol. 2013 Aug 15;380(2):172-84
1*	J:139013 Takatalo M, Jarvinen E, Laitinen S, Thesleff I, Ronnholm R, Expression of the novel Golgi protein GoPro49 is developmentally regulated during mesenchymal differentiation. Dev Dyn. 2008 Aug;237(8):2243-55
1*	J:67784 Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G, Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev. 2001 Feb 15;15(4):467-81
1*	J:20965 Timmons PM, Wallin J, Rigby PW, Balling R, Expression and function of Pax 1 during development of the pectoral girdle. Development. 1994 Oct;120(10):2773-85
1*	J:55583 Tribioli C, Lufkin T, The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen. Development. 1999 Dec;126(24):5699-711
1	J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108
1	J:108573 Tylzanowski P, Mebis L, Luyten FP, The Noggin null mouse phenotype is strain dependent and haploinsufficiency leads to skeletal defects. Dev Dyn. 2006 Jun;235(6):1599-607
1	J:161451 Villavicencio-Lorini P, Kuss P, Friedrich J, Haupt J, Farooq M, Turkmen S, Duboule D, Hecht J, Mundlos S, Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J Clin Invest. 2010 Jun 1;120(6):1994-2004
1*	J:154906 Wang W, Lian N, Li L, Moss HE, Wang W, Perrien DS, Elefteriou F, Yang X, Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development. 2009 Dec;136(24):4143-53
1	J:200760 Wang Y, Zheng Y, Chen D, Chen Y, Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice. Dev Biol. 2013 Sep 15;381(2):301-11
1*	J:195062 Watanabe T, Oyama T, Asada M, Harada D, Ito Y, Inagawa M, Suzuki Y, Sugano S, Katsube K, Karsenty G, Komori T, Kitagawa M, Asahara H, MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development. PLoS Genet. 2013 Jan;9(1):e1003132
1	J:223511 Wei J, Shimazu J, Makinistoglu MP, Maurizi A, Kajimura D, Zong H, Takarada T, Lezaki T, Pessin JE, Hinoi E, Karsenty G, Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation. Cell. 2015 Jun 18;161(7):1576-91
1	J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51
1	J:182757 Wilson DG, Phamluong K, Lin WY, Barck K, Carano RA, Diehl L, Peterson AS, Martin F, Solloway MJ, Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning. Dev Biol. 2012 Mar 15;363(2):413-25
1	J:320420 Yamaguchi H, Kitami M, Uchima Koecklin KH, He L, Wang J, Lagor WR, Perrien DS, Komatsu Y, Temporospatial regulation of intraflagellar transport is required for the endochondral ossification in mice. Dev Biol. 2022 Feb;482:91-100
1*	J:81355 Yang Y, Topol L, Lee H, Wu J, Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation. Development. 2003 Mar;130(5):1003-15
1	J:221866 Yoshida M, Hata K, Takashima R, Ono K, Nakamura E, Takahata Y, Murakami T, Iseki S, Takano-Yamamoto T, Nishimura R, Yoneda T, The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification. Nat Commun. 2015;6:6653
1*	J:28954 Yoshioka H, Iyama K, Inoguchi K, Khaleduzzaman M, Ninomiya Y, Ramirez F, Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1). Dev Dyn. 1995 Sep;204(1):41-7
1*	J:122558 Yu L, Liu H, Yan M, Yang J, Long F, Muneoka K, Chen Y, Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton. Dev Biol. 2007 Jun 15;306(2):549-59
1*	J:75934 Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR, Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr;129(8):1893-904
1	J:331689 Zhang CH, Gao Y, Hung HH, Zhuo Z, Grodzinsky AJ, Lassar AB, Creb5 coordinates synovial joint formation with the genesis of articular cartilage. Nat Commun. 2022 Nov 26;13(1):7295
1	J:233350 Zhang F, Xu L, Xu L, Xu Q, Li D, Yang Y, Karsenty G, Chen CD, JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice. J Mol Cell Biol. 2015 Feb;7(1):23-34
1	J:54915 Zhao Q, Eberspaecher H, Lefebvre V, De Crombrugghe B, Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis. Dev Dyn. 1997 Aug;209(4):377-86
1	J:155388 Zhu H, Bendall AJ, Dlx5 Is a cell autonomous regulator of chondrocyte hypertrophy in mice and functionally substitutes for Dlx6 during endochondral ossification. PLoS One. 2009;4(11):e8097